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Selumetinib Oral Capsule (SELUMETINIB – ORAL)

Selumetinib Oral Capsule (SELUMETINIB - ORAL)

Instructions

Swallow the medicine without crushing or chewing it.

Take on empty stomach - 1 hour before or 2 hours after eating.

Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Drink plenty of water while on this medicine.

Avoid grapefruit and grapefruit juice while on this medicine.

If you vomit after taking a dose, do not take an extra dose. Take your next dose at the usual time.

If you forget to take a dose on time, take it as soon as you remember. If it is less than 6 hours to the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Brand Name(s): Koselugo

Generic Name: Selumetinib

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women must use reliable forms of birth control while taking this medicine and for 1 week after stopping to prevent pregnancy.

Men with a female partner who is of childbearing age must use reliable birth control during sexual activity while taking this medicine and for 1 week after stopping to prevent pregnancy.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • dry skin
  • lack of energy and tiredness
  • nausea and vomiting
  • stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bleeding or bruising
  • persistent diarrhea
  • dizziness
  • dry mouth
  • swelling of the legs, feet, and hands
  • eye pain, redness, or itching
  • rapid heartbeat
  • lightheadedness
  • muscle pain or weakness
  • shortness of breath
  • excessive thirst
  • unusual or unexplained tiredness or weakness
  • difficulty or discomfort urinating
  • blurring or changes of vision
  • seeing halos or colors around lights
  • sudden or unexplained change in weight

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.