Instructions

Swallow the medicine without crushing or chewing it.

Take the medicine with a meal.

Ask your doctor if any of your medicines need to be taken at the same time.

This medicine will work best if you take it at about the same time every day.

Store unopened bottles in the refrigerator. After opening, store the medicine at room temperature away from heat, light, and moisture. Do not store in the bathroom.

Discard any unused medicine 60 days after opening.

This medicine does not stop the spread of viruses that are passed through the blood or during sex.

Always use condoms during sex.

Do not share needles or other personal objects such as shavers or toothbrushes.

This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

This medicine may decrease the effectiveness of some birth controls which use hormones (such as birth control pills and patches). Use an extra form of birth control, such as condoms, while on this medicine.

Use effective birth control to avoid pregnancy.

It is very important that you follow your doctor's instructions for all blood tests.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine may affect areas where fat is stored in the body. This may change your body shape.

Do not use the medication any more than instructed.

Contact your doctor if you notice a change in the amount or darkening of your urine.

It is unknown if this medicine passes into breast milk. Because breast milk may transmit HIV, ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Always refill this medicine before it runs out.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• increased risk of bleeding
• diarrhea
• changes in areas of body fat may alter your body shape
• lack of energy and tiredness
• headaches
• mood changes
• nausea and vomiting
• stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• decreased awareness or responsiveness
• loss of balance
• chest pain
• confusion
• swelling of the legs, feet, and hands
• nosebleeds
• numbness or tingling in hands and feet
• severe or persistent headache
• fast or irregular heart beats
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• loss of movement anywhere on the body
• muscle pain
• muscle trembling or weakness
• red, burning, or itchy skin
• shakiness
• shortness of breath
• red, peeling or blistering skin
• slurred speech
• light colored stool
• symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
• difficulty swallowing
• swelling in the neck or throat
• unsteadiness while walking
• severe or persistent vomiting
• weakness on one side of the body

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.