Instructions

Keep the medicine at room temperature. Avoid heat and direct light.

This medicine is for use in the nose. Avoid getting the medicine into the eyes or mouth. Rinse the eyes with water if the medicine is sprayed into the eyes.

This medicine should be used after a migraine headache starts. It should not be used to prevent a migraine headache.

Ask your doctor, nurse or pharmacist to show you how to use this medicine correctly.

Keep the medicine in the package until you are ready to use it.

Read and carefully follow package instructions for preparing the pump. Do not assemble the pump until you are ready to use it.

If your headache improves but does not completely disappear after taking this medicine, you may need a second dose.

If you need to take a second dose, wait at least 2 hours after taking your first dose.

If your headache does not improve after taking the first dose, do not take a second dose.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Discard any unused medicine 1 hour after opening.

Do not share this medicine with anyone who has not been prescribed this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than twice during 24 hours.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Using this medicine for 10 or more days in a month may make the headaches worse.

If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• constipation
• dizziness or drowsiness
• dry mouth
• lack of energy and tiredness
• feeling of heat or flushing
• numbness or tingling in hands and feet
• hoarseness or throat irritation
• high blood pressure
• irritation inside the nose
• runny nose
• changes in taste or unpleasant taste

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• severe or persistent abdominal pain
• loss of balance
• chest pain
• severe, watery or bloody diarrhea
• fainting
• high fever
• hallucinations (unusual thoughts, seeing or hearing things that are not real)
• cold hands or feet
• fast or irregular heart beats
• mood changes
• muscle cramps
• tight or rigid muscles
• nausea
• pale or blue skin, lips or fingernails
• restlessness
• seizures
• shortness of breath
• stomach pain
• symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
• severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.