Skip to Main Content

Ondansetron Oral Film (ONDANSETRON SOLUBLE FILM – ORAL)

Ondansetron Oral Film (ONDANSETRON SOLUBLE FILM - ORAL)

For nausea or vomiting.

Brand Name(s): Zuplenz

Generic Name: Ondansetron

Instructions

Do not use if the pouch containing the medicine is torn or damaged.

Remove medicine from the foil just before using. Place the sheet on top of your tongue and let it dissolve completely. After it has dissolved, swallow it with saliva.

Only use 1 sheet at a time.

Do not cut the sheet.

Do not chew or swallow it whole.

Wash your hands before and after handling this medicine.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

If you are using this medicine regularly, it is important to take each dose of medicine on time. Keep taking the medicine even if you feel well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting. Do not stand or sit up quickly.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Do not drink beverages with alcohol while on this medicine.

Call the doctor if there are any signs of confusion or unusual changes in behavior.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • constipation
  • dizziness or drowsiness
  • lack of energy and tiredness
  • headaches
  • lightheadedness

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe or persistent abdominal pain
  • agitated feeling or trouble sleeping
  • loss of balance
  • chest pain
  • diarrhea
  • fainting
  • hallucinations (unusual thoughts, seeing or hearing things that are not real)
  • fast, irregular, or slow heartbeat
  • muscle aches, spasms or abnormal movements
  • muscle trembling
  • restlessness
  • blurring or changes of vision
  • severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Ignite Healthwise, LLC.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.