Instructions

This medicine is given as an injection.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

Do not mix this medicine with other solutions.

Always inspect the medicine before using.

The liquid should be clear or light yellow.

Do not use the medicine if it contains any particles or if it has changed color.

Do not shake the medicine before using.

Keep medicine in refrigerator. Do not freeze. If frozen, throw away.

Keep the medicine in its original container.

This medicine may be stored at room temperature for up to 30 days.

Protect medicine from light.

If your medicine is stored in the refrigerator, take it out of the refrigerator about 30 minutes before use to warm to room temperature.

Never use any medicine that has expired.

Discard any remaining medicine after your dose is given.

Wash your hands before and after handling this medicine.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine is associated with an increased risk of blood clots, heart attack, and stroke. Contact your doctor immediately if you experience leg pain or swelling, difficulty breathing, chest or jaw pain, severe headache, one-sided weakness or slurred speech.

Do not use the medication any more than instructed.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Call your doctor right away if you notice any unusual bleeding or bruising.

If you have had a heart attack or a stroke within the past 6 months, talk to your doctor before using this medicine.

Ask your doctor, nurse or pharmacist how to safely discard unused medicines, needles and syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• body aches
• diarrhea
• headaches
• high blood pressure
• pain, redness, swelling near injection
• vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• chest pain
• confusion
• dizziness
• swelling of the legs, feet, and hands
• fainting
• severe or persistent headache
• fast or irregular heart beats
• sudden leg pain, swelling, warmth or redness
• pale or blue skin, lips or fingernails
• seizures
• shortness of breath
• symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
• unusual or unexplained tiredness or weakness
• blurring or changes of vision
• sudden or unexplained weight gain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.