Instructions

Drink the medicine.

This medicine may be taken with or without food.

Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.

Keep the medicine at room temperature. Avoid heat and direct light.

Do not store the medicine in the refrigerator or freezer.

Throw away any medicine left in the open vial after use. Do not save to use later.

This medicine should be used after a migraine headache starts. It should not be used to prevent a migraine headache.

Avoid certain "triggers" to reduce the risk of migraines. Triggers may include red wine, cheese, chocolate, monosodium glutamate, stress or irregular eating or sleeping.

Drink plenty of water while on this medicine.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than once during 24 hours.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.

This medicine may cause bleeding from the stomach or bowels. Stop this medicine and call your doctor right away if you have pain in the stomach, red or dark tarry stools, or vomit that looks like coffee grounds.

Do not use the medication any more than instructed.

Please check with your doctor before drinking alcohol while on this medicine.

Avoid smoking while on this medicine. Smoking may increase your risk for stomach bleeding.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• high blood pressure
• stomach upset or abdominal pain
• changes in taste or unpleasant taste

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• severe or persistent abdominal pain
• bleeding or bruising
• chest or jaw pain
• coughing up blood or vomit that looks like coffee grounds
• swelling of the legs, feet, and hands
• fever
• signs of kidney damage (such as change in urine color or bubbly urine)
• sudden leg pain, swelling, warmth or redness
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• shortness of breath
• bloody or dark, tarry stools
• symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
• difficulty swallowing
• excessive or unusual sweating
• swelling in the neck or throat
• blurring or changes of vision
• severe or persistent vomiting
• sudden or unexplained weight gain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.