Instructions

This medicine is given as an IV injection into a vein.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

The medicine needs to be mixed before being injected.

Follow package direction for diluting medicine with IV fluids or as instructed by your doctor or nurse.

Do not dilute the medicine until ready to use.

Always inspect the medicine before using.

The liquid should be clear or light to dark yellow.

Do not use the medicine if it is cloudy, contains flakes or large particles, or if it has changed color.

Check the medicine before each use. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it.

Keep medicine at room temperature. Protect from light.

Keep the medicine in its original container.

Before medicine is mixed, it may be stored at room temperature - below 77 degrees F (25 degrees C).

Do not store above 77 degrees F (25 degrees C).

Inject the medicine immediately after mixing.

Never use any medicine that has expired.

Discard any unused, mixed medicine after 6 hours.

Discard any unused, mixed medicine after 24 hours in refrigerator.

This medicine should only be used by a person who has been trained to recognize when and how it should be used.

Use this medicine at the same time each day.

Space doses evenly to keep a steady amount of medicine in the body.

You or a family member can be trained to give this medicine at home.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than twice during 24 hours.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Speak with your health care provider before receiving any vaccinations.

Please tell your doctor if you have moderate to severe diarrhea while on this medicine. Do not treat the diarrhea with over-the-counter diarrhea medicine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Ask your doctor, nurse or pharmacist how to safely discard unused medicines, needles and syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• diarrhea
• pain, redness, swelling near injection
• nausea

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• confusion
• severe, watery or bloody diarrhea
• seizures
• shortness of breath
• red, peeling or blistering skin
• yeast infection of mouth
• vaginal itching or yeast infection

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.