Instructions

This medicine is for use in the rectum or around the anus. DO NOT take this medicine by mouth.

Follow the instructions on the package to use this medicine correctly.

Wash your hands before and after using this medicine. However, do not get up right away to wash your hands if you are supposed to lie down for a period of time to give the medicine time to work.

Lie on your left side, with your right knee bent toward your chest. Or, you may kneel on both knees, with your arms folded on the floor with your head resting on your arms.

Unwrap the suppository and moisten it with a few drops of cool water. Insert the pointed end into the anus, and push it all the way in with your finger.

If your dose is one-half (1/2) suppository, carefully cut it lengthwise using a clean, sharp knife.

If you have hemorrhoids, you may coat the tip of the suppository with a water-soluble lubricant (for example K-Y Jelly) before inserting. Do NOT use Vaseline.

Next, lie on your left side for at least 30 minutes, and keep the medicine in your rectum for at least 1 hour or, preferably, overnight.

Keep this medicine in the refrigerator.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Tell your doctor if symptoms do not get better or if they get worse.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Do not freeze the medicine.

Cautions

IMPORTANT: Children and teenagers should not use medications containing aspirin for cold and flu symptoms or chickenpox.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

There is an increased risk of bleeding while on this medicine, please tell your doctor or nurse if you notice any excessive bleeding or bruising.

Do not use the medication any more than instructed.

If you drink alcohol regularly, please speak with your doctor.

Do not breastfeed while on this medicine. This medicine can pass through breast milk to the baby.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• rectal burning or irritation

If you have any of the following side effects, you may be getting too much medicine. Please contact your doctor to let them know about these side effects.

• ringing in the ears

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• severe or persistent abdominal pain
• coughing up blood or vomit that looks like coffee grounds
• fever
• swelling in the neck or throat
• signs of kidney damage (such as change in urine color or bubbly urine)
• bloody or dark, tarry stools

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.