Instructions

This medicine is given gradually through the IV line.

Carefully follow the instructions for preparing this medicine before injection.

Always inspect the medicine before using.

The liquid should be colorless to yellow-green in color.

Do not use the medicine if it contains any particles or if it has changed color.

Store at room temperature or in refrigerator. Do not freeze. Protect from light.

Never use any medicine that has expired.

Drink extra water while on this medicine. Adults should try to drink 6-8 cups (48 to 64 oz.) of water every day.

This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Few patients may experience tendon problems. This is more common in patients older than 60. If you notice pain, swelling, or difficulty moving your joints, tell your doctor. This can happen even after stopping the medicine for a few months.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

Speak with your health care provider before receiving any vaccinations.

Please tell your doctor if you have moderate to severe diarrhea while on this medicine. Do not treat the diarrhea with over-the-counter diarrhea medicine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• agitated feeling or trouble sleeping
• diarrhea
• dizziness
• pain, redness, swelling near injection
• nausea and vomiting
• stomach upset or abdominal pain
• yeast infection of mouth
• vaginal itching or yeast infection

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• bleeding or bruising
• chest pain
• confusion
• severe, watery or bloody diarrhea
• fainting
• flu-like symptoms
• numbness or tingling in hands and feet
• severe or persistent headache
• fast or irregular heart beats
• pain in the joints
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• mood changes
• muscle trembling
• seizures
• shortness of breath
• red, peeling or blistering skin
• light colored stool
• difficulty or discomfort urinating
• urinating less often
• blood in urine
• severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.