Instructions

This medicine is given as an IV injection into a vein.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

This medicine should be given by a trained health care provider.

After using this medicine, drink fluids as directed by your doctor to help clear the medicine from the body.

Drink at least 2 glasses of water before treatment, unless instructed otherwise.

It may take several weeks for this medicine to fully work.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

This medicine may affect the strength of your bones. If you have or are at increased risk for osteoporosis (weakening of the bones), your doctor may recommend foods with calcium and vitamin D.

Visit your dentist regularly. Proper care of your teeth is very important while taking this medicine. Brush your teeth and floss regularly.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

This medicine can cause birth defects. Speak with your doctor about birth control methods that should be used while on this medicine and for some time after stopping it.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting. Do not stand or sit up quickly.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Avoid smoking while on this medicine. Smoking may increase your risk for bone fractures.

If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Do not breastfeed while on this medicine.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• dizziness
• lack of energy and tiredness
• flu-like symptoms
• headaches
• pain, redness, swelling near injection
• nausea

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• bone pain
• fever or chills
• numbness or tingling in hands and feet
• fast or irregular heart beats
• jaw pain
• signs of kidney damage (such as change in urine color or bubbly urine)
• mouth sores or irritation
• muscle cramps or weakness
• tight or rigid muscles
• joint or muscle pain
• eye pain or swelling
• red, burning, or itchy skin
• redness of eyes
• seizures
• sensitivity to light
• shortness of breath
• skin tingling, burning or prickly feeling
• unusual or unexplained tiredness or weakness
• blurring or changes of vision
• weakness

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.