Instructions

This is an IV medicine. It is given through a sterile tube directly into the vein by a healthcare provider.

This medicine is given gradually through the IV line.

You must be monitored by a health care professional during and after each dose is given.

Drink plenty of water while on this medicine.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Your doctor should check you for hepatitis before you start this medicine and while you are using it. Tell your doctor if you are being treated for hepatitis or any other infection.

This medicine may rarely cause a life-threatening brain infection. Get medical help right away if you have weakness on one side of the body, loss of coordination, vision problems, changes in thinking or memory, confusion, or personality changes.

This medicine is associated with a rare, but serious problem of the liver. Speak to your doctor about the early signs of liver problems and the benefits and risks of using this medicine.

Tell your doctor or nurse right away if fever, chills, flushing, dizziness, fainting, pounding or irregular heartbeat, wheezing or trouble breathing, back pain, stomach pain, chest pain, rash, or itching start while the medicine is being given. It may need to be stopped or given at a slower rate.

This medicine may cause dizziness or fainting. Do not stand or sit up quickly.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Always carry an ID card or wear a medical alert bracelet indicating your medical condition.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• agitated feeling or trouble sleeping
• diarrhea
• swelling of the legs, feet, and hands
• lack of energy and tiredness
• nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• severe or persistent abdominal pain
• decreased appetite
• back pain
• loss of balance
• bleeding or bruising
• changes in memory, mood, or thinking
• confusion
• fever or chills
• signs of kidney damage (such as change in urine color or bubbly urine)
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• muscle aches, spasms or abnormal movements
• pale or blue skin, lips or fingernails
• seizures
• sore throat
• difficulty speaking
• unsteadiness while walking
• blurring or changes of vision
• severe or persistent vomiting
• weakness on one side of the body

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.